FGF-2 Polyclonal Antibody
¥680.00
Manic Fringe Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614821
- 产品信息
商品描述
靶点-Target
Manic Fringe
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110
特异性
Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.
基因名称
MFNG
蛋白名称
Beta-1,3-N-acetylglucosaminyltransferase manic fringe
别名
MFNG;Beta-1;3-N-acetylglucosaminyltransferase manic fringe;O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Organism-1
Human
基因ID-1
4242
SwissProt-1
O00587
Organism-2
Mouse
基因ID-2
17305
SwissProt-2
O09008
背景
This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],
细胞定位
Golgi apparatus membrane ; Single-pass type II membrane protein .
