FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MAN1B1
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from MAN1B1 . at AA range: 100-180
特异性
MAN1B1 Polyclonal Antibody detects endogenous levels of MAN1B1 protein.
基因名称
MAN1B1
蛋白名称
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
别名
MAN1B1;Endoplasmic reticulum mannosyl-oligosaccharide 1;2-alpha-mannosidase;ER alpha-1,2-mannosidase;ER mannosidase 1;ERMan1;Man9GlcNAc2-specific-processing alpha-mannosidase;Mannosidase alpha class 1B member 1
Organism-1
Human
基因ID-1
11253
SwissProt-1
Q9UKM7
Organism-2
Mouse
SwissProt-2
A2AJ15
背景
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011],
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
