FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MADD
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
183kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MADD. AA range:751-800
特异性
MADD Polyclonal Antibody detects endogenous levels of MADD protein.
基因名称
MADD
蛋白名称
MAP kinase-activating death domain protein
别名
MADD;DENN;IG20;KIAA0358;MAP kinase-activating death domain protein;Differentially expressed in normal and neoplastic cells;Insulinoma glucagonoma clone 20;Rab3 GDP/GTP exchange factor
Organism-1
Human
基因ID-1
8567
SwissProt-1
Q8WXG6
Organism-2
Mouse
基因ID-2
228355
SwissProt-2
Q80U28
Organism-3
Rat
基因ID-3
94193
SwissProt-3
O08873
背景
Tumor necrosis factor alpha (TNF-alpha) is a signaling molecule that interacts with one of two receptors on cells targeted for apoptosis. The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins. The protein encoded by this gene is a death domain-containing adaptor protein that interacts with the death domain of TNF-alpha receptor 1 to activate mitogen-activated protein kinase (MAPK) and propagate the apoptotic signal. It is membrane-bound and expressed at a higher level in neoplastic cells than in normal cells. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane . Cytoplasm . Cell projection, axon .
