FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Mad 4
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
24kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MAD4. AA range:10-59
特异性
Mad 4 Polyclonal Antibody detects endogenous levels of Mad 4 protein.
基因名称
MXD4
蛋白名称
Max dimerization protein 4
别名
MXD4;BHLHC12;MAD4;Max dimerization protein 4;Max dimerizer 4;Class C basic helix-loop-helix protein 12;bHLHc12;Max-associated protein 4;Max-interacting transcriptional repressor MAD4
Organism-1
Human
基因ID-1
10608
SwissProt-1
Q14582
Organism-2
Mouse
SwissProt-2
Q60948
背景
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .
