FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
mAChR M1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
51kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human CHRM1. AA range:295-344
特异性
mAChR M1 Polyclonal Antibody detects endogenous levels of mAChR M1 protein.
基因名称
CHRM1
蛋白名称
Muscarinic acetylcholine receptor M1
别名
CHRM1;Muscarinic acetylcholine receptor M1
Organism-1
Human
基因ID-1
1128
SwissProt-1
P11229
Organism-2
Mouse
基因ID-2
12669
SwissProt-2
P12657
Organism-3
Rat
基因ID-3
25229
SwissProt-3
P08482
背景
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
