- 产品信息
商品描述
靶点-Target
LRP3
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66
特异性
LRP3 Polyclonal Antibody detects endogenous levels of LRP3 protein.
基因名称
LRP3
蛋白名称
Low-density lipoprotein receptor-related protein 3
别名
LRP3;Low-density lipoprotein receptor-related protein 3;LRP-3;105 kDa low-density lipoprotein receptor-related protein;hLRp105
Organism-1
Human
基因ID-1
4037
SwissProt-1
O75074
Organism-3
Rat
基因ID-3
89787
SwissProt-3
O88204
背景
function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,
细胞定位
Membrane ; Single-pass type I membrane protein . Membrane, coated pit .





