FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Lck
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
56kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Lck. AA range:161-210
特异性
Lck Polyclonal Antibody detects endogenous levels of Lck protein.
基因名称
LCK
蛋白名称
Tyrosine-protein kinase Lck
别名
LCK;Tyrosine-protein kinase Lck;Leukocyte C-terminal Src kinase;LSK;Lymphocyte cell-specific protein-tyrosine kinase;Protein YT16;Proto-oncogene Lck;T cell-specific protein-tyrosine kinase;p56-LCK
Organism-1
Human
基因ID-1
3932
SwissProt-1
P06239
Organism-2
Mouse
基因ID-2
16818
SwissProt-2
P06240
Organism-3
Rat
基因ID-3
313050
SwissProt-3
Q01621
背景
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016],
细胞定位
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytosol . Present in lipid rafts in an inactive form. .
