FGF-2 Polyclonal Antibody
¥680.00
Latrophilin-1 Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614737
- 产品信息
商品描述
靶点-Target
Latrophilin-1
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
163kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LPHN1. AA range:561-610
特异性
Latrophilin-1 Polyclonal Antibody detects endogenous levels of Latrophilin-1 protein.
基因名称
LPHN1
蛋白名称
Latrophilin-1
别名
LPHN1;KIAA0821;LEC2;Latrophilin-1;Calcium-independent alpha-latrotoxin receptor 1;CIRL-1;Lectomedin-2
Organism-1
Human
基因ID-1
22859
SwissProt-1
O94910
Organism-2
Mouse
基因ID-2
330814
SwissProt-2
Q80TR1
Organism-3
Rat
基因ID-3
65096
SwissProt-3
O88917
背景
This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell projection, axon . Cell projection, growth cone . Cell junction, synapse . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, synaptosome . Colocalizes with TENM2 on the cell surface, across intercellular junctions and on nerve terminals near synaptic clefts. .
