FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LAT
反应性
Human,Rat,Mouse,
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LAT. AA range:86-135
特异性
LAT Polyclonal Antibody detects endogenous levels of LAT protein.
基因名称
LAT
蛋白名称
Linker for activation of T-cells family member 1
别名
LAT;Linker for activation of T-cells family member 1;36 kDa phospho-tyrosine adapter protein;pp36;p36-38
Organism-1
Human
基因ID-1
27040
SwissProt-1
O43561
Organism-2
Mouse
SwissProt-2
O54957
背景
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type III membrane protein . Present in lipid rafts.
