FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
LARG
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
173kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498
特异性
LARG Polyclonal Antibody detects endogenous levels of LARG protein.
基因名称
ARHGEF12
蛋白名称
Rho guanine nucleotide exchange factor 12
别名
ARHGEF12;KIAA0382;LARG;Rho guanine nucleotide exchange factor 12;Leukemia-associated RhoGEF
Organism-1
Human
基因ID-1
23365
SwissProt-1
Q9NZN5
Organism-2
Mouse
SwissProt-2
Q8R4H2
背景
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
细胞定位
Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .
