FGF-2 Polyclonal Antibody
¥680.00
Laminin-R Polyclonal Antibody
活动价：
¥680.00
市场价：¥880.00
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产品规格：
- 50μL
- 100μL
货号：
FAB2614729
- 产品信息
商品描述
靶点-Target
Laminin-R
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Laminin-R. AA range:166-215
特异性
Laminin-R Polyclonal Antibody detects endogenous levels of Laminin-R protein.
基因名称
RPSA
蛋白名称
40S ribosomal protein SA
别名
RPSA;LAMBR;LAMR1;40S ribosomal protein SA;37 kDa laminin receptor precursor;37LRP;37/67 kDa laminin receptor;LRP/LR;67 kDa laminin receptor;67LR;Colon carcinoma laminin-binding protein;Laminin receptor 1;LamR;Laminin-binding pr
Organism-1
Human
基因ID-1
3921
SwissProt-1
P08865
Organism-2
Mouse
基因ID-2
100505031
SwissProt-2
P14206
Organism-3
Rat
基因ID-3
29236
SwissProt-3
P38983
背景
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in
细胞定位
Cell membrane. Cytoplasm. Nucleus . 67LR is found at the surface of the plasma membrane, with its C-terminal laminin-binding domain accessible to extracellular ligands. 37LRP is found at the cell surface, in the cytoplasm and in the nucleus (By similarity). Colocalizes with PPP1R16B in the cell membrane. .
