Laminin α-2 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614721

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商品描述
  • 靶点-Target

    Laminin α-2

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    343kD

  • 推荐稀释比

    IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human LAMA2. AA range:2011-2060

  • 特异性

    Laminin α-2 Polyclonal Antibody detects endogenous levels of Laminin α-2 protein.

  • 基因名称

    LAMA2

  • 蛋白名称

    Laminin subunit alpha-2

  • 别名

    LAMA2;LAMM;Laminin subunit alpha-2;Laminin M chain;Laminin-12 subunit alpha;Laminin-2 subunit alpha;Laminin-4 subunit alpha;Merosin heavy chain

  • Organism-1

    Human

  • 基因ID-1

    3908

  • SwissProt-1

    P24043

  • Organism-2

    Mouse

  • SwissProt-2

    Q60675

  • 背景

    Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Secreted, extracellular space, extracellular matrix, basement membrane. Major component.