Laminin α-2 Polyclonal Antibody
活动价:
市场价:¥880.00
- 50μL
- 100μL
FAB2614721
- 产品信息
商品描述
靶点-Target
Laminin α-2
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
343kD
推荐稀释比
IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LAMA2. AA range:2011-2060
特异性
Laminin α-2 Polyclonal Antibody detects endogenous levels of Laminin α-2 protein.
基因名称
LAMA2
蛋白名称
Laminin subunit alpha-2
别名
LAMA2;LAMM;Laminin subunit alpha-2;Laminin M chain;Laminin-12 subunit alpha;Laminin-2 subunit alpha;Laminin-4 subunit alpha;Merosin heavy chain
Organism-1
Human
基因ID-1
3908
SwissProt-1
P24043
Organism-2
Mouse
SwissProt-2
Q60675
背景
Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane. Major component.





