FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KV8.2
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KCNV2. AA range:187-236
特异性
KV8.2 Polyclonal Antibody detects endogenous levels of KV8.2 protein.
基因名称
KCNV2
蛋白名称
Potassium voltage-gated channel subfamily V member 2
别名
KCNV2;Potassium voltage-gated channel subfamily V member 2;Voltage-gated potassium channel subunit Kv8.2
Organism-1
Human
基因ID-1
169522
SwissProt-1
Q8TDN2
Organism-2
Mouse
基因ID-2
240595
SwissProt-2
Q8CFS6
背景
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
