- 产品信息
商品描述
靶点-Target
KV1.5
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
68kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KCNA5. AA range:253-302
特异性
KV1.5 Polyclonal Antibody detects endogenous levels of KV1.5 protein.
基因名称
KCNA5
蛋白名称
Potassium voltage-gated channel subfamily A member 5
别名
KCNA5;Potassium voltage-gated channel subfamily A member 5;HPCN1;Voltage-gated potassium channel HK2;Voltage-gated potassium channel subunit Kv1.5
Organism-1
Human
基因ID-1
3741
SwissProt-1
P22460
Organism-2
Mouse
基因ID-2
16493
SwissProt-2
Q61762
Organism-3
Rat
基因ID-3
25470
SwissProt-3
P19024
背景
Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of
细胞定位
Cell membrane ; Multi-pass membrane protein .





