FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KPI-2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
164kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LMTK2. AA range:651-700
特异性
KPI-2 Polyclonal Antibody detects endogenous levels of KPI-2 protein.
基因名称
LMTK2
蛋白名称
Serine/threonine-protein kinase LMTK2
别名
LMTK2;AATYK2;BREK;KIAA1079;KPI2;LMR2;Serine/threonine-protein kinase LMTK2;Apoptosis-associated tyrosine kinase 2;Brain-enriched kinase;hBREK;CDK5/p35-regulated kinase;CPRK;Kinase/phosphatase/inhibitor 2;Lemur tyrosine kinase 2
Organism-1
Human
基因ID-1
22853
SwissProt-1
Q8IWU2
Organism-2
Mouse
SwissProt-2
Q3TYD6
背景
The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009],
细胞定位
Membrane ; Multi-pass membrane protein .
