FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KOR-1
反应性
Human,Mouse,Rat,Monkey
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370
特异性
KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.
基因名称
OPRK1
蛋白名称
Kappa-type opioid receptor
别名
OPRK1;OPRK;Kappa-type opioid receptor;K-OR-1;KOR-1
Organism-1
Human
基因ID-1
4986
SwissProt-1
P41145
Organism-2
Mouse
基因ID-2
18387
SwissProt-2
P33534
Organism-3
Rat
基因ID-3
29335
SwissProt-3
P34975
背景
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],
细胞定位
Cell membrane ; Multi-pass membrane protein .
