FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KLHL3
反应性
Human,Rat,Mouse,
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59
特异性
KLHL3 Polyclonal Antibody detects endogenous levels of KLHL3 protein.
基因名称
KLHL3
蛋白名称
Kelch-like protein 3
别名
KLHL3;KIAA1129;Kelch-like protein 3
Organism-1
Human
基因ID-1
26249
SwissProt-1
Q9UH77
Organism-2
Mouse
SwissProt-2
E0CZ16
背景
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],
细胞定位
Cytoplasm, cytoskeleton . Cytoplasm, cytosol .
