FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KIR2.3
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
50kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KCNJ4. AA range:251-300
特异性
KIR2.3 Polyclonal Antibody detects endogenous levels of KIR2.3 protein.
基因名称
KCNJ4
蛋白名称
Inward rectifier potassium channel 4
别名
KCNJ4;IRK3;Inward rectifier potassium channel 4;HIRK2;HRK1;Hippocampal inward rectifier;HIR;Inward rectifier K;+;channel Kir2.3;IRK-3;Potassium channel;inwardly rectifying subfamily J member 4
Organism-1
Human
基因ID-1
3761
SwissProt-1
P48050
Organism-2
Mouse
SwissProt-2
P52189
Organism-3
Rat
基因ID-3
116649
SwissProt-3
P52190
背景
Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle membrane . TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization. .
