- 产品信息
商品描述
靶点-Target
KCNT1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
140kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KCNT1. AA range:1019-1068
特异性
KCNT1 Polyclonal Antibody detects endogenous levels of KCNT1 protein.
基因名称
KCNT1
蛋白名称
Potassium channel subfamily T member 1
别名
KCNT1;KIAA1422;Potassium channel subfamily T member 1;KCa4.1
Organism-1
Human
基因ID-1
57582
SwissProt-1
Q5JUK3
Organism-2
Mouse
基因ID-2
227632
SwissProt-2
Q6ZPR4
Organism-3
Rat
基因ID-3
60444
SwissProt-3
Q9Z258
背景
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],
细胞定位
Cell membrane ; Multi-pass membrane protein .





