KCNT1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614666

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商品描述
  • 靶点-Target

    KCNT1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    140kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human KCNT1. AA range:1019-1068

  • 特异性

    KCNT1 Polyclonal Antibody detects endogenous levels of KCNT1 protein.

  • 基因名称

    KCNT1

  • 蛋白名称

    Potassium channel subfamily T member 1

  • 别名

    KCNT1;KIAA1422;Potassium channel subfamily T member 1;KCa4.1

  • Organism-1

    Human

  • 基因ID-1

    57582

  • SwissProt-1

    Q5JUK3

  • Organism-2

    Mouse

  • 基因ID-2

    227632

  • SwissProt-2

    Q6ZPR4

  • Organism-3

    Rat

  • 基因ID-3

    60444

  • SwissProt-3

    Q9Z258

  • 背景

    Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .