FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
JIK
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
110kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human TAOK3. AA range:531-580
特异性
JIK Polyclonal Antibody detects endogenous levels of JIK protein.
基因名称
TAOK3
蛋白名称
Serine/threonine-protein kinase TAO3
别名
TAOK3;DPK;JIK;KDS;MAP3K18;Serine/threonine-protein kinase TAO3;Cutaneous T-cell lymphoma-associated antigen HD-CL-09;CTCL-associated antigen HD-CL-09;Dendritic cell-derived protein kinase;JNK/SAPK-inhibitory kinase;Jun kinase-inhi
Organism-1
Human
基因ID-1
51347
SwissProt-1
Q9H2K8
Organism-2
Mouse
基因ID-2
330177
SwissProt-2
Q8BYC6
Organism-3
Rat
基因ID-3
304530
SwissProt-3
Q53UA7
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Also localized to the peripheral cell membrane.,subunit:Self-associates.,tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.,
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein . Also localized to the peripheral cell membrane.
