- 产品信息
商品描述
靶点-Target
JAK1
反应性
Human,Mouse,Rat
应用
IF,WB,IP,IHC,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
132kD
推荐稀释比
IF 1:50-200;WB 1:200-1:1000;IHC 1:100-1:300;ELISA 1:10000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human JAK1. AA range:988-1037
特异性
JAK1 Polyclonal Antibody detects endogenous levels of JAK1 protein.
基因名称
JAK1
蛋白名称
Tyrosine-protein kinase JAK1
别名
JAK1;JAK1A;JAK1B;Tyrosine-protein kinase JAK1;Janus kinase 1;JAK-1
Organism-1
Human
基因ID-1
3716
SwissProt-1
P23458
Organism-2
Mouse
SwissProt-2
P52332
背景
This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
Endomembrane system; Peripheral membrane protein. Wholly intracellular, possibly membrane associated.





