FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IRAK-M
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
68kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IRAK3. AA range:491-540
特异性
IRAK-M Polyclonal Antibody detects endogenous levels of IRAK-M protein.
基因名称
IRAK3
蛋白名称
Interleukin-1 receptor-associated kinase 3
别名
IRAK3;Interleukin-1 receptor-associated kinase 3;IRAK-3;IL-1 receptor-associated kinase M;IRAK-M
Organism-1
Human
基因ID-1
11213
SwissProt-1
Q9Y616
Organism-2
Mouse
SwissProt-2
Q8K4B2
背景
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
细胞定位
Cytoplasm . Nucleus . In dendritic cells, translocates into the nucleus upon IL33 stimulation. .
