- 产品信息
商品描述
靶点-Target
IQGAP1
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
190kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
特异性
IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.
基因名称
IQGAP1
蛋白名称
Ras GTPase-activating-like protein IQGAP1
别名
IQGAP1;KIAA0051;Ras GTPase-activating-like protein IQGAP1;p195
Organism-1
Human
基因ID-1
8826
SwissProt-1
P46940
Organism-2
Mouse
基因ID-2
29875
SwissProt-2
Q9JKF1
背景
IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .





