IQGAP1 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614616

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商品描述
  • 靶点-Target

    IQGAP1

  • 反应性

    Human,Mouse

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    190kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296

  • 特异性

    IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.

  • 基因名称

    IQGAP1

  • 蛋白名称

    Ras GTPase-activating-like protein IQGAP1

  • 别名

    IQGAP1;KIAA0051;Ras GTPase-activating-like protein IQGAP1;p195

  • Organism-1

    Human

  • 基因ID-1

    8826

  • SwissProt-1

    P46940

  • Organism-2

    Mouse

  • 基因ID-2

    29875

  • SwissProt-2

    Q9JKF1

  • 背景

    IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .