- 产品信息
商品描述
靶点-Target
IP3KA
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445
特异性
IP3KA Polyclonal Antibody detects endogenous levels of IP3KA protein.
基因名称
ITPKA
蛋白名称
Inositol-trisphosphate 3-kinase A
别名
ITPKA;Inositol-trisphosphate 3-kinase A;Inositol 1;4,5-trisphosphate 3-kinase A;IP3 3-kinase A;IP3K A;InsP 3-kinase A
Organism-1
Human
基因ID-1
3706
SwissProt-1
P23677
Organism-2
Mouse
基因ID-2
228550
SwissProt-2
Q8R071
Organism-3
Rat
基因ID-3
81677
SwissProt-3
P17105
背景
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.[provided by RefSeq, Apr 2011],
细胞定位
Cytoplasm, cytoskeleton .





