FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
INPP5J
反应性
Human,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
107kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from INPP5J . at AA range: 850-930
特异性
INPP5J Polyclonal Antibody detects endogenous levels of INPP5J protein.
基因名称
INPP5J
蛋白名称
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
别名
INPP5J;PIB5PA;PIPP;Phosphatidylinositol 4;5-bisphosphate 5-phosphatase A;Inositol polyphosphate 5-phosphatase J
Organism-1
Human
基因ID-1
27124
SwissProt-1
Q15735
Organism-2
Mouse
SwissProt-2
P59644
Organism-3
Rat
基因ID-3
171088
SwissProt-3
Q9JMC1
背景
catalytic activity:1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.,catalytic activity:D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-bisphosphate + phosphate.,domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.,function:Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.,PTM:Phosphorylated at Ser/Thr residues.,similarity:Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.,subcellular location:Predominantly localized to membrane ruffles.,
细胞定位
Cytoplasm . Predominantly localized to membrane ruffles. .
