FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ILT-3
反应性
Human
应用
IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
49kD
推荐稀释比
IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human LILRB4. AA range:201-250
特异性
ILT-3 Polyclonal Antibody detects endogenous levels of ILT-3 protein.
基因名称
LILRB4
蛋白名称
Leukocyte immunoglobulin-like receptor subfamily B member 4
别名
LILRB4;ILT3;LIR5;Leukocyte immunoglobulin-like receptor subfamily B member 4;CD85 antigen-like family member K;Immunoglobulin-like transcript 3;ILT-3;Leukocyte immunoglobulin-like receptor 5;LIR-5;Monocyte inhibitory receptor HM18;
Organism-1
Human
基因ID-1
11006
SwissProt-1
Q8NHJ6
Organism-2
Mouse
SwissProt-2
Q64281
背景
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2
细胞定位
Cell membrane ; Single-pass type I membrane protein . Ligand binding leads to internalization and translocation to an antigen-processing compartment. .
