FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-4
反应性
Human,Mouse
应用
WB,Flow Cyt,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
18kD
推荐稀释比
WB 1:500-2000;Flow Cyt 1:50-200;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from the C-terminal region of human IL-4.
特异性
IL-4 Polyclonal Antibody detects endogenous levels of IL-4 protein.
基因名称
IL4
蛋白名称
Interleukin-4
别名
IL4;Interleukin-4;IL-4;B-cell stimulatory factor 1;BSF-1;Binetrakin;Lymphocyte stimulatory factor 1;Pitrakinra
Organism-1
Human
基因ID-1
3565
SwissProt-1
P05112
Organism-2
Mouse
SwissProt-2
P07750
背景
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
细胞定位
Secreted.
