FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-17RC
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770
特异性
IL-17RC Polyclonal Antibody detects endogenous levels of IL-17RC protein.
基因名称
IL17RC
蛋白名称
Interleukin-17 receptor C
别名
IL17RC;Interleukin-17 receptor C;IL-17 receptor C;IL-17RC;Interleukin-17 receptor homolog;IL17Rhom;Interleukin-17 receptor-like protein;IL-17RL;ZcytoR14
Organism-1
Human
基因ID-1
84818
SwissProt-1
Q8NAC3
Organism-2
Mouse
SwissProt-2
Q8K4C2
背景
This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Soluble isoforms may be produced.
