IL-12A Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614561

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商品描述
  • 靶点-Target

    IL-12A

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    25kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC:1:50-300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human IL-12A. AA range:16-65

  • 特异性

    IL-12A Polyclonal Antibody detects endogenous levels of IL-12A protein.

  • 基因名称

    IL12A

  • 蛋白名称

    Interleukin-12 subunit alpha

  • 别名

    IL12A;NKSF1;Interleukin-12 subunit alpha;IL-12A;Cytotoxic lymphocyte maturation factor 35 kDa subunit;CLMF p35;IL-12 subunit p35;NK cell stimulatory factor chain 1;NKSF1

  • Organism-1

    Human

  • 基因ID-1

    3592

  • SwissProt-1

    P29459

  • Organism-2

    Mouse

  • 基因ID-2

    16159

  • SwissProt-2

    P43431

  • Organism-3

    Rat

  • 基因ID-3

    84405

  • SwissProt-3

    Q9R103

  • 背景

    This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Secreted .