FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
IL-10Rα
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
63kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IL-10R alpha. AA range:462-511
特异性
IL-10Rα Polyclonal Antibody detects endogenous levels of IL-10Rα protein.
基因名称
IL10RA
蛋白名称
Interleukin-10 receptor subunit alpha
别名
IL10RA;IL10R;Interleukin-10 receptor subunit alpha;IL-10 receptor subunit alpha;IL-10R subunit alpha;IL-10RA;CDw210a;Interleukin-10 receptor subunit 1;IL-10R subunit 1;IL-10R1;CD antigen CD210
Organism-1
Human
基因ID-1
3587
SwissProt-1
Q13651
Organism-2
Mouse
SwissProt-2
Q61727
背景
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009],
细胞定位
Cell membrane ; Single-pass type I membrane protein. Cytoplasm .
