- 产品信息
商品描述
靶点-Target
IgA
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276
特异性
IgA Polyclonal Antibody detects endogenous levels of IgA protein.
基因名称
IGHA1/IGHA2
蛋白名称
Ig alpha-1 chain C region/Ig alpha-2 chain C region
别名
IGHA1;Ig alpha-1 chain C region;IGHA2;Ig alpha-2 chain C region
Organism-1
Human
基因ID-1
3493;3494
SwissProt-1
P01876;P01877
背景
disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,
细胞定位
Secreted . Cell membrane .





