- 产品信息
商品描述
靶点-Target
HRT2
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
36kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HEY2. AA range:21-70
特异性
HRT2 Polyclonal Antibody detects endogenous levels of HRT2 protein.
基因名称
HEY2
蛋白名称
Hairy/enhancer-of-split related with YRPW motif protein 2
别名
HEY2;BHLHB32;CHF1;GRL;HERP;HERP1;HRT2;Hairy/enhancer-of-split related with YRPW motif protein 2;Cardiovascular helix-loop-helix factor 1;hCHF1;Class B basic helix-loop-helix protein 32;bHLHb32;HES-related repressor protein 2;Ha
Organism-1
Human
基因ID-1
23493
SwissProt-1
Q9UBP5
Organism-2
Mouse
基因ID-2
15214
SwissProt-2
Q9QUS4
背景
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





