- 产品信息
商品描述
靶点-Target
HRI
反应性
Human,Mouse,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
71kD
推荐稀释比
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human EIF2AK1. AA range:571-620
特异性
HRI Polyclonal Antibody detects endogenous levels of HRI protein.
基因名称
EIF2AK1
蛋白名称
Eukaryotic translation initiation factor 2-alpha kinase 1
别名
EIF2AK1;HRI;KIAA1369;Eukaryotic translation initiation factor 2-alpha kinase 1;Heme-controlled repressor;HCR;Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase;Heme-regulated inhibitor;Hemin-sensitive initiation factor 2
Organism-1
Human
基因ID-1
27102
SwissProt-1
Q9BQI3
Organism-2
Mouse
基因ID-2
15467
SwissProt-2
Q9Z2R9
背景
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],
细胞定位
cytoplasm,





