FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HPK1
反应性
Human,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
91kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human MEKKK 1. AA range:371-420
特异性
HPK1 Polyclonal Antibody detects endogenous levels of HPK1 protein.
基因名称
MAP4K1
蛋白名称
Mitogen-activated protein kinase kinase kinase kinase 1
别名
MAP4K1;HPK1;Mitogen-activated protein kinase kinase kinase kinase 1;Hematopoietic progenitor kinase;MAPK/ERK kinase kinase kinase 1;MEK kinase kinase 1;MEKKK 1
Organism-1
Human
基因ID-1
11184
SwissProt-1
Q92918
Organism-2
Mouse
基因ID-2
26411
SwissProt-2
P70218
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP3K1.,tissue specificity:Expressed primarily in hematopoietic organs, including bone marrow, spleen and thymus. Also expressed at very low levels in lung, kidney, mammary glands and small intestine.,
细胞定位
intracellular,cytoplasm,membrane,
