- 产品信息
商品描述
靶点-Target
HoxD10
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
32kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HOXD10. AA range:291-340
特异性
HoxD10 Polyclonal Antibody detects endogenous levels of HoxD10 protein.
基因名称
HOXD10
蛋白名称
Homeobox protein Hox-D10
别名
HOXD10;HOX4D;HOX4E;Homeobox protein Hox-D10;Homeobox protein Hox-4D;Homeobox protein Hox-4E
Organism-1
Human
基因ID-1
3236
SwissProt-1
P28358
Organism-2
Mouse
基因ID-2
15430
SwissProt-2
P28359
背景
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.





