- 产品信息
商品描述
靶点-Target
hnRNP Q
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
62kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human hnRNP Q. AA range:236-285
特异性
hnRNP Q Polyclonal Antibody detects endogenous levels of hnRNP Q protein.
基因名称
SYNCRIP
蛋白名称
Heterogeneous nuclear ribonucleoprotein Q
别名
SYNCRIP;HNRPQ;NSAP1;Heterogeneous nuclear ribonucleoprotein Q;hnRNP Q;Glycine- and tyrosine-rich RNA-binding protein;GRY-RBP;NS1-associated protein 1;Synaptotagmin-binding;cytoplasmic RNA-interacting protein
Organism-1
Human
基因ID-1
10492
SwissProt-1
O60506
Organism-2
Mouse
基因ID-2
56403
SwissProt-2
Q7TMK9
Organism-3
Rat
基因ID-3
363113
SwissProt-3
Q7TP47
背景
This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011],
细胞定位
Cytoplasm . Microsome . Endoplasmic reticulum . Nucleus . The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). .; [Isoform 1]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .; [Isoform 2]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .; [Isoform 3]: Nucleus, nucleoplasm . Expressed predominantly in the nucleoplasm. .





