- 产品信息
商品描述
靶点-Target
hnRNP M
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
78kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human hnRNP M. AA range:11-60
特异性
hnRNP M Polyclonal Antibody detects endogenous levels of hnRNP M protein.
基因名称
HNRNPM
蛋白名称
Heterogeneous nuclear ribonucleoprotein M
别名
HNRNPM;HNRPM;NAGR1;Heterogeneous nuclear ribonucleoprotein M;hnRNP M
Organism-1
Human
基因ID-1
4670
SwissProt-1
P52272
Organism-2
Mouse
基因ID-2
76936
SwissProt-2
Q9D0E1
Organism-3
Rat
基因ID-3
116655
SwissProt-3
Q62826
背景
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provide
细胞定位
Nucleus, nucleolus .





