- 产品信息
商品描述
靶点-Target
hnRNP F
反应性
Human,Mouse,Rat
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human hnRNP F. AA range:11-60
特异性
hnRNP F Polyclonal Antibody detects endogenous levels of hnRNP F protein.
基因名称
HNRNPF
蛋白名称
Heterogeneous nuclear ribonucleoprotein F
别名
HNRNPF;HNRPF;Heterogeneous nuclear ribonucleoprotein F;hnRNP F;Nucleolin-like protein mcs94-1
Organism-1
Human
基因ID-1
3185
SwissProt-1
P52597
Organism-2
Mouse
基因ID-2
98758
SwissProt-2
Q9Z2X1
Organism-3
Rat
基因ID-3
64200
SwissProt-3
Q794E4
背景
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, nucleoplasm.





