- 产品信息
商品描述
靶点-Target
hnRNP DL
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
46kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HNRPDL. AA range:241-290
特异性
hnRNP DL Polyclonal Antibody detects endogenous levels of hnRNP DL protein.
基因名称
HNRPDL
蛋白名称
Heterogeneous nuclear ribonucleoprotein D-like
别名
HNRPDL;JKTBP;Heterogeneous nuclear ribonucleoprotein D-like;hnRNP D-like;hnRNP DL;AU-rich element RNA-binding factor;JKT41-binding protein;Protein laAUF1
Organism-1
Human
基因ID-1
9987
SwissProt-1
O14979
Organism-2
Mouse
SwissProt-2
Q9Z130
Organism-3
Rat
基因ID-3
305178
SwissProt-3
Q3SWU3
背景
heterogeneous nuclear ribonucleoprotein D like(HNRNPDL) Homo sapiens This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member
细胞定位
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner. .





