FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
hnRNP D0
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
38kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human hnRPD. AA range:49-98
特异性
hnRNP D0 Polyclonal Antibody detects endogenous levels of hnRNP D0 protein.
基因名称
HNRNPD
蛋白名称
Heterogeneous nuclear ribonucleoprotein D0
别名
HNRNPD;AUF1;HNRPD;Heterogeneous nuclear ribonucleoprotein D0;hnRNP D0;AU-rich element RNA-binding protein 1
Organism-1
Human
基因ID-1
3184
SwissProt-1
Q14103
Organism-2
Mouse
基因ID-2
11991
SwissProt-2
Q60668
Organism-3
Rat
基因ID-3
79256
SwissProt-3
Q9JJ54
背景
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are nucleic acid binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It localizes to both the nucleus and the cytoplasm. This protein is implicated in the regulation of mRNA stability. Alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Cytoplasmic localization oscillates diurnally.
