FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HNF4α
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HNF4 alpha. AA range:280-329
特异性
HNF-4α Polyclonal Antibody detects endogenous levels of HNF-4α protein.
基因名称
HNF4A
蛋白名称
Hepatocyte nuclear factor 4-alpha
别名
HNF4A;HNF4;NR2A1;TCF14;Hepatocyte nuclear factor 4-alpha;HNF-4-alpha;Nuclear receptor subfamily 2 group A member 1;Transcription factor 14;TCF-14;Transcription factor HNF-4
Organism-1
Human
基因ID-1
3172
SwissProt-1
P41235
Organism-2
Mouse
基因ID-2
15378
SwissProt-2
P49698
Organism-3
Rat
基因ID-3
25735
SwissProt-3
P22449
背景
The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012],
细胞定位
Nucleus.
