- 产品信息
商品描述
靶点-Target
HMG-2
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
27kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180
特异性
HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.
基因名称
HMGB2
蛋白名称
High mobility group protein B2
别名
HMGB2;HMG2;High mobility group protein B2;High mobility group protein 2;HMG-2
Organism-1
Human
基因ID-1
3148
SwissProt-1
P26583
Organism-2
Mouse
基因ID-2
97165
SwissProt-2
P30681
Organism-3
Rat
基因ID-3
29395
SwissProt-3
P52925
背景
This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Chromosome . Cytoplasm . Secreted . In basal state predominantly nuclear. .





