FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HLA-DOα
反应性
Human
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HLA-DOA. AA range:71-120
特异性
HLA-DOα Polyclonal Antibody detects endogenous levels of HLA-DOα protein.
基因名称
HLA-DOA
蛋白名称
HLA class II histocompatibility antigen DO alpha chain
别名
HLA-DOA;HLA-DNA;HLA-DZA;HLA class II histocompatibility antigen;DO alpha chain;MHC DN-alpha;MHC DZ alpha;MHC class II antigen DOA
Organism-1
Human
基因ID-1
3111
SwissProt-1
P06340
背景
HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008],
细胞定位
Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
