FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Hint1
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HINT1. AA range:71-120
特异性
Hint1 Polyclonal Antibody detects endogenous levels of Hint1 protein.
基因名称
HINT1
蛋白名称
Histidine triad nucleotide-binding protein 1
别名
HINT1;HINT;PKCI1;PRKCNH1;Histidine triad nucleotide-binding protein 1;Adenosine 5'-monophosphoramidase;Protein kinase C inhibitor 1;Protein kinase C-interacting protein 1;PKCI-1
Organism-1
Human
基因ID-1
3094
SwissProt-1
P49773
Organism-2
Mouse
基因ID-2
15254
SwissProt-2
P70349
Organism-3
Rat
基因ID-3
690660
SwissProt-3
P62959
背景
This gene encodes a protein that hydrolyzes purine nucleotide phosphoramidates substrates, including AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif. This gene is considered a tumor suppressor gene. In addition, mutations in this gene can cause autosomal recessive neuromyotonia and axonal neuropathy. There are several related pseudogenes on chromosome 7. Several transcript variants have been observed. [provided by RefSeq, Dec 2015],
细胞定位
Cytoplasm . Nucleus . Interaction with CDK7 leads to a more nuclear localization. .
