- 产品信息
商品描述
靶点-Target
Hec1
反应性
Human,Mouse
应用
WB,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
73kD
推荐稀释比
WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human KNTC2. AA range:351-400
特异性
Hec1 Polyclonal Antibody detects endogenous levels of Hec1 protein.
基因名称
NDC80
蛋白名称
Kinetochore protein NDC80 homolog
别名
NDC80;HEC;HEC1;KNTC2;Kinetochore protein NDC80 homolog;Highly expressed in cancer protein;Kinetochore protein Hec1;HsHec1;Kinetochore-associated protein 2;Retinoblastoma-associated protein HEC
Organism-1
Human
基因ID-1
10403
SwissProt-1
O14777
Organism-2
Mouse
基因ID-2
67052
SwissProt-2
Q9D0F1
背景
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011],
细胞定位
Nucleus . Chromosome, centromere, kinetochore . Localizes to kinetochores from late prophase to anaphase (PubMed:14699129). Localizes specifically to the outer plate of the kinetochore (PubMed:14699129). .





