HC-II Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614406

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商品描述
  • 靶点-Target

    HC-II

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    60kD

  • 推荐稀释比

    WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II. AA range:41-90

  • 特异性

    HC-II Polyclonal Antibody detects endogenous levels of HC-II protein.

  • 基因名称

    SERPIND1

  • 蛋白名称

    Heparin cofactor 2

  • 别名

    SERPIND1;HCF2;Heparin cofactor 2;Heparin cofactor II;HC-II;Protease inhibitor leuserpin-2;HLS2;Serpin D1

  • Organism-1

    Human

  • 基因ID-1

    3053

  • SwissProt-1

    P05546

  • Organism-2

    Mouse

  • 基因ID-2

    15160

  • SwissProt-2

    P49182

  • Organism-3

    Rat

  • 基因ID-3

    79224

  • SwissProt-3

    Q64268

  • 背景

    This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015],

  • 细胞定位

    extracellular region,extracellular space,extracellular exosome,