- 产品信息
商品描述
靶点-Target
HC-II
反应性
Human,Mouse,Rat
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
60kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II. AA range:41-90
特异性
HC-II Polyclonal Antibody detects endogenous levels of HC-II protein.
基因名称
SERPIND1
蛋白名称
Heparin cofactor 2
别名
SERPIND1;HCF2;Heparin cofactor 2;Heparin cofactor II;HC-II;Protease inhibitor leuserpin-2;HLS2;Serpin D1
Organism-1
Human
基因ID-1
3053
SwissProt-1
P05546
Organism-2
Mouse
基因ID-2
15160
SwissProt-2
P49182
Organism-3
Rat
基因ID-3
79224
SwissProt-3
Q64268
背景
This gene belongs to the serpin gene superfamily. Serpins play roles in many processes including inflammation, blood clotting, and cancer metastasis. Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity. This gene encodes a plasma serine protease that functions as a thrombin and chymotrypsin inhibitor. The protein is activated by heparin, dermatan sulfate, and glycosaminoglycans. Allelic variations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2015],
细胞定位
extracellular region,extracellular space,extracellular exosome,





