FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
hCAP-H
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
83kD
推荐稀释比
WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human NCAPH. AA range:441-490
特异性
hCAP-H Polyclonal Antibody detects endogenous levels of hCAP-H protein.
基因名称
NCAPH
蛋白名称
Condensin complex subunit 2
别名
NCAPH;BRRN;BRRN1;CAPH;KIAA0074;Condensin complex subunit 2;Barren homolog protein 1;Chromosome-associated protein H;hCAP-H;Non-SMC condensin I complex subunit H;XCAP-H homolog
Organism-1
Human
基因ID-1
23397
SwissProt-1
Q15003
Organism-2
Mouse
SwissProt-2
Q8C156
背景
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013],
细胞定位
Nucleus . Cytoplasm . Chromosome . In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
