- 产品信息
商品描述
靶点-Target
HBP1
反应性
Human,Mouse,Rat,Monkey
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human HBP1. AA range:431-480
特异性
HBP1 Polyclonal Antibody detects endogenous levels of HBP1 protein.
基因名称
HBP1
蛋白名称
HMG box-containing protein 1
别名
HBP1;HMG box-containing protein 1;HMG box transcription factor 1;High mobility group box transcription factor 1
Organism-1
Human
基因ID-1
26959
SwissProt-1
O60381
Organism-2
Mouse
基因ID-2
73389
SwissProt-2
Q8R316
Organism-3
Rat
基因ID-3
27080
SwissProt-3
Q62661
背景
function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,similarity:Contains 1 AXH domain.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.,
细胞定位
Nucleus .





