- 产品信息
商品描述
靶点-Target
GUF1
反应性
Human,Mouse
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
74kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470
特异性
GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.
基因名称
GUF1
蛋白名称
Translation factor GUF1 mitochondrial
别名
GUF1;Translation factor GUF1;mitochondrial;Elongation factor 4 homolog;EF-4;GTPase GUF1;Ribosomal back-translocase
Organism-1
Human
基因ID-1
60558
SwissProt-1
Q8N442
Organism-2
Mouse
SwissProt-2
Q8C3X4
背景
This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
细胞定位
Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .





