GUF1 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2614387

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商品描述
  • 靶点-Target

    GUF1

  • 反应性

    Human,Mouse

  • 应用

    IHC,IF,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    74kD

  • 推荐稀释比

    IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    The antiserum was produced against synthesized peptide derived from human GUF1. AA range:421-470

  • 特异性

    GUF1 Polyclonal Antibody detects endogenous levels of GUF1 protein.

  • 基因名称

    GUF1

  • 蛋白名称

    Translation factor GUF1 mitochondrial

  • 别名

    GUF1;Translation factor GUF1;mitochondrial;Elongation factor 4 homolog;EF-4;GTPase GUF1;Ribosomal back-translocase

  • Organism-1

    Human

  • 基因ID-1

    60558

  • SwissProt-1

    Q8N442

  • Organism-2

    Mouse

  • SwissProt-2

    Q8C3X4

  • 背景

    This gene encodes a GTPase that triggers back-translocation of the elongating ribosome during mitochondrial protein synthesis. The protein contains a highly conserved C-terminal domain not found in other GTPases that facilitates tRNA binding. The encoded protein is thought to prevent misincorporation of amino acids in stressful, suboptimal conditions. An allelic variant in this gene has been associated with early infantile epileptic encephalopathy-40. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],

  • 细胞定位

    Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .