- 产品信息
商品描述
靶点-Target
GROα
反应性
Human,Mouse,Rat
应用
IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
11kD
推荐稀释比
IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
The antiserum was produced against synthesized peptide derived from human GROalpha. AA range:39-88
特异性
GROα Polyclonal Antibody detects endogenous levels of GROα protein.
基因名称
CXCL1
蛋白名称
Growth-regulated alpha protein
别名
CXCL1;GRO;GRO1;GROA;MGSA;SCYB1;Growth-regulated alpha protein;C-X-C motif chemokine 1;GRO-alpha;1-73;Melanoma growth stimulatory activity;MGSA;Neutrophil-activating protein 3;NAP-3
Organism-1
Human
基因ID-1
2919
SwissProt-1
P09341
Organism-2
Mouse
基因ID-2
14825
SwissProt-2
P12850
Organism-3
Rat
基因ID-3
81503
SwissProt-3
P14095
背景
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014],
细胞定位
Secreted.





